GOING ABOVE AND BEYOND
RESEARCH SERVICES
In Vitro ADME/Tox
Compound Purity, Solubility, Dissolution and Chemical Stability
- Caco-2 Permeability
- Metabolic Stability
- CYP450 Inhibition
- CYP450 Induction
- CYP450 Phenotyping
- UGT Inhibition
- UGT Phenotyping
- Uptake Transporter Inhibition
- Uptake Transporter Phenotyping
- Efflux Transporter Inhibition
- Efflux Transporter Phenotyping
- Additional Drug-Metabolizing Enzyme Phenotyping (FMOs, MAOs, AOs, ALDH, ADH)
- Plasma or Whole Blood Stability
- Blood-to-Plasma Partitioning
- Plasma Protein Binding
- Tissue Binding
- Drug Metabolite Profiling and Structural Identification
- GSH Trapping for Reactive Metabolites Formation
- Cytotoxicity
- Hemolysis